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Lizinna

An alternative to Cilest

from

Lizinna is a combined contraceptive pill, which is 99% effective at preventing pregnancy. 

It’s made up of 2 artificial versions of the hormones oestrogen and progesterone. 

Lizinna can be ordered online using a straightforward questionnaire, as long you are female and aged between 16 and 50. Our doctors will review your order and approve the best treatment.

We can deliver your pills to you, or you can collect them in any Superdrug store or from a post office.

Last reviewed: 04-06-2020 by Dr Simran Deo

3 Month Course - Start Order

6 Month Course - Start Order

To place an order, fill in a brief questionnaire. One of our doctors will review your order and prescribe a suitable treatment.


3 months (63 tablets) £25.00
6 months (126 tablets) £35.00

Prices include prescription and delivery.

In a hurry? Choose Click and Collect and pick up your order after just 4 hours from a Superdrug Pharmacy.

Delivery options

Delivery method Cost Estimated delivery

You will choose your delivery option at the checkout. Delivery options may vary depending on the pack size and dosage chosen.

About Lizinna

Combined pills like Lizinna prevent pregnancy in 3 ways:

  • stopping your ovaries from releasing an egg (ovulation) each month
  • thickening the mucus at the entrance of the womb (cervix), so there’s less chance for sperm to reach an egg
  • thinning the lining of your womb so it’s harder for a fertilised egg to implant and grow

Lizinna, like other combined pills, is 99% effective in preventing pregnancy, if taken at the same time every day. 

Although this may reduce to 91% effectiveness if you:

  • forget to take your pill
  • do not to restart the pill pack at the correct time
  • happen to be sick (vomit) or have diarrhoea 
  • take other medicines that make the pill less effective

Lizinna comes in a strip of 21 pills, with each pill marked with a day of the week.

  1. take the 1st pill on the 1st day of your period
  2. remember to take your pill at the same time every day 
  3. be sure to take the pill marked with the correct day of the week 
  4. take a 7 day break before starting your next pack

During the 7 day break, you’ll get what is known as a ‘withdrawal bleed’ which is like a period

You do not need to use extra contraception during the 7 day break. But you should make sure you start the next strip of pills on time to continue being protected from pregnancy. 

Read more about how to take Lizinna.

What should I do if I miss a pill?

  • If you miss your pill and remember within 24 hours, take it as soon as you remember. Take the next pill at the usual time. You will still be protected from getting pregnant
  • If you forget to take your pill for more 24 hours, your protection from pregnancy may be reduced. See our doctor’s guidance for more information if you haven’t taken a pill in the last 24 hours

Other ways of taking Lizinna

There are other ways of taking Lizinna which are safe, but are not mentioned in the patient information leaflet. You can:

  • take 1 pill a day for 9 weeks then no pills for the next 7 days, or you can take a 4 day break
  • take 1 pill a day every day with no break

We suggest that you talk to your GP to decide which is the best way for you to take Lizinna.


Start taking Lizinna in the 1st 5 days of your period, and you will be protected against pregnancy straight away. 

But if you start taking Lizinna any time after day 5 of your period, you’re only protected once you have taken it every day for 7 days in a row. During these first 7 days, you will need to use condoms to protect against pregnancy.

There may be some side effects when you take Lizinna, though not everyone will get them. 

If you have minor side effects, it’s recommended that you:

  • continue taking the pill for 3 months, since the effects might go away as your body gets used to the pill
  • talk to a doctor if the side effects continue for longer than 3 months or become difficult to deal with 
Your doctor will check whether anything else could be causing your side effects or making them worse. They might suggest another form of contraception.

Common side effects:

  • headache
  • migraine
  • nausea
  • breast pain
  • mood changes
  • changes in your period
  • vaginal discharge
  • vaginal thrush infection

Uncommon side effects:

  • acne 
  • eczema
  • changes in blood pressure
  • vomiting
  • diarrhoea
  • hair loss
  • breast enlargement 
  • fluid retention
  • changes in libido
  • changes in weight to less or more

Rare side effects:

  • blood clots
  • asthma
  • hypersensitivity
  • nipple discharge 
  • reduced hearing
  • skin changes

Will I gain weight on Lizinna?

The patient information leaflet lists weight gain as a common side effect, although in fact some women have found they lose weight while taking Lizinna. There is no scientific evidence to connect use of the combined pill and weight gain.

Lizinna may not be suitable for you if you’re allergic to any of its ingredients, or if you:

  • are a smoker and are over the age of 35 
  • take medications such as statins for high cholesterol
  • have a raised BMI/are very overweight
  • have a history of migraines with aura
  • have a history of heart attacks or strokes
  • have heart disease, circulation problems or have a history/family history of blood clotting

Other conditions which may make Lizinna unsuitable for you are:

  • depression
  • a history of breast cancer (but Lizinna can be used after 5 years if there is no evidence of disease and non-hormonal methods are unsuitable)
  • cervical cancer
  • uncontrolled diabetes
  • varicose veins
  • kidney or liver problems
  • Crohn's disease or inflammatory bowel disease
  • sickle cell anaemia
  • lupus
  • epilepsy
  • unexplained vaginal bleeding

If you suffer from any of these conditions, it could be that a progesterone-only (mini pill) is a better option, but you should always discuss this with the doctor who is prescribing you the pill. They’ll be able to help you choose a suitable form of contraception.

Before you start taking Lizinna, talk to your doctor about any other medicines you’re taking, because some can make the pill less effective. 

These include:

  • blood pressure medication
  • anti-epileptics
  • anti-virals to treat HIV or hepatitis C
  • anti-fungals  
  • antibiotics to treat tuberculosis (TB)
  • immunosuppressants for arthritis
  • herbal treatments like St John’s wort

If you're prescribed a short course (up to 2 months) of any of these medicines while you're taking Lizinna, your doctor might suggest that you use a different form of contraception for a while. 

See the patient information leaflet for a full list of the drugs that might interact with Lizinna.  

Lizinna may increase your chances of having the following conditions:

  • blood clots (thrombosis) – because Lizinna contains oestrogen, there a slight increase in the risk of blood clots with this pill. Common symptoms of blood lots to look out for are sharp chest pains, coughing up blood, getting swollen and painful legs, and having a sudden rapid heartbeat or breathing
  • breast cancer – because combined pills contain oestrogen, they can also increase the speed at which breast cells grow. This can lead to an increased risk of getting breast cancer. It's important to check for breast lumps often, whether you are taking a contraceptive pill or not, and you need to tell your doctor about any lumps you find
  • cervical cancer – the oestrogen in the combined pill can also cause some cancer-promoting DNA to become more active, which can lead to an increased risk of getting cervical cancer. Whether you are using a contraceptive with oestrogen in or not, you should get regular cervical screenings. The NHS offers cervical screening for women aged 25 to 64, to help catch any unusual cell changes in the cervix

Talk to your GP if you're worried about the potential health risks of using Lizinna.

Can I drink alcohol on Lizinna?

You can drink alcohol while you're taking Lizinna – drinking alcohol will not make the pill less effective and it will not increase any possible side effects.

It's best though for health reasons to stick to the recommended alcohol limits

Can I take painkillers on Lizinna?

You can take over the counter painkillers such as ibuprofen or paracetamol if you’re on a combined pill. These will not make the contraception less effective and they also will not increase the chance of side effects.

Can I take the morning after pill on Lizinna?

You can take the morning after pill (ellaOne or Levonelle) if you’re taking Lizinna. 

You need to wait for 5 days after taking the ellaOne emergency contraceptive before you start Lizinna. It's important to use a contraceptive like condoms for at least 12 days after you take ellaOne.

If you take the Levonelle emergency contraceptive, you can restart Lizinna straight away. You will need to use condoms for at least 7 days after taking Levonelle, or until you have used your Lizinna for 7 days in a row.

Can I delay my period when I’m taking Lizinna?

It is simple to delay your period when you’re taking a combined pill such as Lizinna – you just need to skip the usual 7 day break between packs.
You should not take period delay tablets if you’re already taking Lizinna.

Can I take Lizinna if I’m breastfeeding?

It is not recommended that you take Lizinna if you are breastfeeding as this can be dangerous for your baby. You can find out about alternative forms of contraception such as barrier methods – including condoms – by talking to your doctor.

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