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Pack of Zyban 150mg 60 tablets to help quit smoking

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Quit Smoking with Zyban

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Pack of Zyban 150mg 60 tablets to help quit smoking

Zyban is a medication that helps you to quit smoking by reducing nicotine withdrawal symptoms, such as cravings and headaches. Zyban contains the active substance bupropion. It reduces nicotine withdrawal symptoms and needs to be taken for a duration of several weeks. 

Due to exceptionally high demand this product currently isn’t in stock.

To place an order, fill in a brief questionnaire. One of our doctors will review your order and prescribe a suitable treatment. You will only be charged if treatment is prescribed.


Zyban (150mg) - 60 tablets £69.50

In a hurry? Choose Click and Collect and pick up your order after just 2 hours from a Superdrug Pharmacy.

Delivery options

Delivery method Cost Estimated delivery

You will choose your delivery option at the checkout. Delivery options may vary depending on the pack size and dosage chosen.

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About Zyban

How does Zyban work?

Zyban is an antidepressant that works by reducing nicotine withdrawal symptoms when you’re trying to quit smoking, though the exact way it helps to stop smoking is unknown. Most smokers struggle with withdrawal symptoms when they stop smoking, such as anxiety, irritability headaches, and nicotine cravings. 

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How is Zyban taken?

Start taking Zyban one to two weeks before your set date for stopping smoking. During the first week of taking Zyban, you need to take one tablet containing a dose of 150mg bupropion. On your 7th day of treatment, increase your dosage to two 150mg tablets per day, taken at least 8 hours apart (but not before going to sleep in the evening). Continue this dose for a maximum period of 9 weeks.

If you have not successfully stopped smoking by week 7, speak to your doctor. You may need to stop taking Zyban. If you have stopped smoking, you can gradually stop taking Zyban during week 7 - 9. Speak to your doctor to discuss the duration of your treatment.

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Who should not take Zyban?

Do not take Zyban if:

  • you are allergic to bupropion or any other ingredient in Zyban
  • you are taking any other medication which contains bupropion
  • you suffer from seizures (for example epilepsy)
  • you have a brain tumour
  • you have severe liver problems
  • you are a heavy drinker who has recently stopped or is planning to stop drinking
  • you have recently stopped taking sedatives or medication used to treat anxiety
  • you are taking sedatives or medication used to treat anxiety and are planning to stop taking it
  • you suffer from bipolar disorder
  • you are taking medication for Parkinson’s disease (or have recently taken any)

Discuss your medical history with a doctor before taking Zyban or any other bupropion medication. It is particularly important that you mention any mental health issues you suffer from or have suffered from in the past. For a full list of warnings and risks, please read the Zyban patient leaflet that comes with your medication.

Zyban interacts with a range of medicines. Tell your doctor about all prescription and non-prescription medications you are currently taking or have recently taken before beginning your treatment.

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Zyban Side Effects

Very common Zyban side effects

  • insomnia (difficulty sleeping)
Do not take Zyban in the evening or before bedtime as this increases the risk of sleeping difficulties.

Common side effects

  • feelings of depression
  • anxiety
  • problems with concentration
  • tremor (feeling shaky)
  • nausea and vomiting
  • headache
  • stomach problems
  • changes in taste
  • dry mouth
  • fever
  • dizziness
  • skin rash
  • sweating
  • itching

 Uncommon side effects

  • increase in blood pressure
  • flushing
  • visual disturbances
  • loss of appetite
  • chest pain
  • feeling weak
  • confusion
  • rapid heart beat

How long do Zyban side effects last?

The side effects of Zyban usually happen in the first few weeks of taking it, and should go away during the course of treatment as your body gets used to the medication. If your side effects last for longer than 3 months, or if they are causing you to worry, then speak to your doctor about changing your dosage or switching to a different medication.

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