Tadalafil (Generic Cialis)

Tadalafil (Generic Cialis)

Tadalafil tablets treat erectile dysfunction by making it easier to get and stay hard. They come as either daily tablets, so you're always ready, or on-demand, where you take them 30-60 minutes before sex. Tadalafil works for 60-70% of men.

In stock
from £27.00

Product details

Tadalafil tablets are used to treat erectile dysfunction in men. Tadalafil is available to buy discreetly online, in ‘daily’ or ‘on demand’ dosages from Superdrug Online Doctor.

Tadalafil is very effective for most men and can last for up to 36 hours.

Dr Simran Deo Medical Editor

Medically reviewed by

Dr Simran Deo

Last reviewed: 28 Oct 2020

Tadalafil prices

Starting prices for the different pack sizes. Available Tadalafil dosages are 2.5mg, 5mg, 10mg and 20mg.

Pack Size Price
4 tablets from £27.00
8 tablets from £46.00
12 tablets from £62.00
16 tablets from £80.00
28 tablets from £54.99
40 tablets from £200.00
56 tablets from £280.00

How it Works

Tadalafil (Generic Cialis)

What is tadalafil (generic Cialis)?

Tadalafil is a prescription medication for erectile dysfunction. It is a type of medication known as a PDE-5 inhibitor, and helps men to get an erection when they are unable to naturally. Tadalafil works in the same way as Cialis, but can be manufactured by any pharmaceutical company. This means that tadalafil is usually available at a lower price than Cialis. which is also used to treat erectile dysfunction.

How tadalafil works

Tadalafil works similarly to other erectile dysfunction medications, such as Viagra and Cialis. It works by relaxing the muscles and blood vessels in your penis, improving blood flow and making it easier to get and keep erections when you’re aroused. It is a type of medication known as a PDE-5 inhibitor, which blocks certain enzymes that can make it difficult to get an erection. Tadalafil, as well as other erectile dysfunction treatments, only help you get an erection when you are sexually aroused. It does not give you an erection on its own.

Does tadalafil make you last longer?

Yes, tadalafil can help you last longer if you are finding it difficult to keep an erection during sex. However, it has no effect on how long it takes you to orgasm, so tadalafil will not help if you are orgasming too quickly. If you are finishing too quickly, you may want to look into techniques on how to last longer in bed, or treatment for premature ejaculation.

How to take tadalafil

You should take one tablet of tadalafil at least 30 minutes to an hour before sex, to give the medication time to start working. If you have sex more than twice a week, you may want to try a lower daily dosage of tadalafil (2.5mg or 5mg). With the lower dosages, you take it at the same time every day so the effects are always working, and you don’t need to take it just before having sex. This is useful for men who have sex often, or who enjoy spontaneous sex without having to remember to take a pill before having sex.

When taking tadalafil, swallow the tablet whole with a glass of water.

For the best results, avoid eating a heavy meal or fatty foods before taking tadalafil. These foods can slow down how quickly your body absorbs the medication, which can make it take longer to start working. Alcohol can also make tadalafil less effective, and can increase the likelihood of side effects.

How long does tadalafil last?

The effects of tadalafil lasts for up to 36 hours after you take it, which is why it is sometimes called the “Weekend Pill”. This means that tadalafil will help you to get an erection when you’re sexually aroused during this time frame, and not that you’ll have an erection that lasts for 36 hours.

Daily doses of tadalafil are designed so the medication is always working, so you’ll be able to get an erection when you need one.

Reviews of tadalafil

Tadalafil is an effective medication:

  • 60-70% of men find tadalafil works for them
  • Less than 2% of men reported experiencing mild side effects when taking tadalafil, so it is fairly safe to use for most men
  • Our tadalafil service has a rating of 4.3 out of 5 on Trustpilot.com
  • Tadalafil has a rating of 8.5 out of 10 on drugs.com
  • Tadalafil takes about 30 mins to start working
  • Tadalafil lasts for up to 36 hours

Dosages of tadalafil

There are 4 dosages of tadalafil. 2 daily doses and 2 doses taken before sex. Daily doses can be a better choice if you have sex on more than 3 different days a week.

Make sure to check with a doctor before switching the dose of any medication.

Tadalafil 2.5mg:

  • The lowest dosage of tadalafil
  • You can try this dose if you’ve tried 5mg and it worked well but it gives you some mild side effects
  • This dose is slightly less effective that 5mg, but it also has a lower chance of side effects

Tadalafil 5mg:

  • The standard daily dose
  • This is the recommended dose if you’ve not tried a daily dosage of tadalafil before

Tadalafil 10mg:

  • The standard before sex dose
  • This is the recommended dose if you’ve not tried tadalafil before

Tadalafil 20mg:

  • The higher-strength before sex dose
  • You could try this dose if 10mg does not work for you and you don’t get any serious side effects
  • This dose is slightly more likely to work than 10mg, but has a higher risk of side effects.

Tadalafil vs Cialis

If you’re not sure which to choose, remember they both have the same active ingredient and both are safe as long as a doctor approves treatment for you. We don’t recommend one over the other.

Tadalafil and Cialis comparison

Tadalafil vs Cialis Tadalafil Cialis
Effective for... 60-70% of users 60-70% of users
Our Trustpilot rating 4.3 out of 5 4.6 out of 5
Drugs.com rating 8.5 8.7
Can you buy online? Yes Yes
Available on NHS prescription Yes Only for some people
Available dosages 2.5mg, 5mg, 10mg, 20mg 2.5mg, 5mg, 10mg, 20mg
How fast do they work? 30 mins* 30 mins*
How long do they last? Up to 36 hours* Up to 36 hours*

* these time apply to 10mg or 20mg doses you take before sex – daily doses are always working

Tadalafil vs sildenafil

If you need help choosing:

  • Both are about as effective as each other – even though sildenafil has higher dosage numbers, that doesn’t mean it’s stronger overall
  • If you want a longer-lasting medication, you might want to choose tadalafil or tadalafil daily
  • If you don’t want to have to plan to take your medication before sex, you might want to choose tadalafil daily

Since sildenafil and tadalafil are the active ingredients in Viagra and Cialis, you can see our Viagra vs Cialis vs Levitra page for more information.

Sildenafil and tadalafil comparison

Tadalafil vs Sildenafil Tadalafil Sildenafil
Effective for... 60-70% of users 74% of users
Our Trustpilot rating 4.3 out of 5 4.6 out of 5
Drugs.com rating 8.5 8.2
Over the counter version No Viagra Connect
Daily dosage? Yes No
Available dosages 2.5mg, 5mg, 10mg, 20mg 25mg, 50mg, 100mg
How fast do they work? 30 mins* 30 to 60 mins
How long do they last? Up to 36 hours* 4 to 6 hours

* these time apply to 10mg or 20mg doses you take before sex – daily doses are always working

Tadalafil safety information

Before taking any medication, you should read the safety advice in the patient information leaflet that comes with it. Tadalafil is only available on prescription and is not suitable for everyone, as it may cause side effects.

You can read more information about how to take tadalafil, how to store it and the full list of known side effects in the patient information leaflet.

Tadalafil side effects

Less than 2% of men get side effects from tadalafil. If you experience any side effects when taking tadalafil, do not change your dose or stop taking the medication without speaking with your doctor first.

Some common side effects of tadalafil include:

  • Headaches
  • Muscle pain
  • Back pain
  • Indigestion
  • Flushing on your face

Some uncommon side effects of tadalafil include:

  • Feeling dizzy
  • Stomach pain
  • Fast heartbeat (palpitations)
  • Changes in blood pressure
  • Nausea and vomiting
  • Prolonged painful erection
  • Nose bleeds
  • Tiredness
  • Ringing in the ears
  • Eye pain
  • Blurred vision
  • Difficulty breathing

Some rare side effects of tadalafil are:

  • Fainting
  • Seizure
  • Temporary memory loss
  • Sweating
  • Swollen eyelids
  • Hives on the skin
  • Loss of hearing
  • Blood in semen

If you experience any of the following severe side effects, stop taking tadalafil and seek medical help immediately:

  • Allergic reactions like wheezing, chest tightening, rashes, swelling of the eyes and face
  • Sudden loss of vision
  • Seizures
  • A prolonged painful erection (a condition known as priapism)

Tadalafil and other medications

Some medications may interact with tadalafil and cause dangerous side effects, and some may affect how well tadalafil works. You should tell your doctor if you are taking any of the following medicines:

  • Alpha blockers like tamsulosin, alfuzosin or doxazosin (used to treat prostate enlargement and high blood pressure)
  • Blood pressure medicines
  • Nitrate medicines (used to treat angina, including GTN spray or tablets)
  • Antipsychotic medicines like phenytoin
  • Antibiotics such as rifampicin, erythromycin
  • Medicines for treating HIV or AIDS
  • Medicines for treating fungal infections
  • Other ED pills like Viagra


Tadalafil (2019) NHS [accessed 14 August 2020]

Tadalafil (2019) Drugs.com [accessed 14 August 2020]

Tadalafil (2019) EMC [accessed 14 August 2020]

The efficacy and safety of tadalafil: an update (2004) NJUI [accessed 28 October 2020]

Patient Reviews