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pack of 4 tablets spedra 200mg

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Order Avanafil Online


Avanafil (Spedra) stands out from other erectile dysfunction medication because it can start working in only 15 minutes. Out of the erectile dysfunction tablets on the market, it was invented most recently and was design to:

  • Be fast-acting; AND
  • Have fewer side effects
If you are interested in ordering Avanafil, start a free assessment with us, place your order, and your online doctor can check if it's the right medication for you.

4 tablets from £49
8 tablets from £89

100mg and 200mg tablets available

In a hurry? Choose Click and Collect and pick up your order after just 3 hours from a Superdrug Pharmacy.

Delivery options

Delivery method Cost Estimated delivery

You will choose your delivery option at the checkout. Delivery options may vary depending on the pack size and dosage chosen.

About Avanafil

What is Avanafil?

Avanafil is a medicine used in the treatment of erectile dysfunction (ED). Like Viagra, it is a type of ‘PDE-5 inhibitor’ (an oral medicine used to treat ED). PDE-5 inhibitors are usually the first option for the medical treatment of ED. 

Avanafil was approved for use in the UK in 2012, and was designed to be quick-acting and highly selective as a medicine (this means there is a bigger increase in the effect of the medication as you increase the dose). Avanafil is the active ingredient in the drugs Spedra and Stendra.

Avanafil can be a great choice for men who:

  • Have had their eyesight affected by other PDE-5 inhibitors.
  • Want a medication that works quickly.
  • Don't want to worry as much about drinking or diet affecting their medication.
The table below shows Avanafil compared to Cialis and Viagra:

Avanafil Cialis Viagra
How quickly does it start working? 15-30 mins 30 mins 60 mins
How long does it last? Over 6 hours
24-36 hours
4-6 hours
Can it affect your eyesight? No
Yes Yes
Is it strongly affected by alcohol or fatty foods? No Yes Yes

What is the difference between Avanafil, Stendra, and Spedra?

Avanafil is the generic name for this medicine, so ‘Avanafil’ is also the name of the active ingredient in the medicine.. Stendra and Spedra are both brand names of Avanafil but, medically speaking, they are all the same. 

Avanafil was originally only sold under a branded name, like Sildenafil (Viagra), so only one company could set the price. Now the patent for its name has since run out, and Avanafil is available in its cheaper, unbranded form.

Spedra is the most common brand of Avanafil in England, and Stendra is more common in the US. Avanafil, Stendra, and Spedra are all licensed for use in the treatment of erectile dysfunction in the UK.

What do reviews of Avanafil say?

The reviews for Avanafil have all been broadly positive. The medicine is relatively new at 5 years old, but it has already proven to be a highly effective form of treatment for ED that doesn't bother users too much with side effects.

Avanafil won’t be suitable for every person. Some of the benefits seen by reviewers were that it is:

  • Fast-acting – 15-30 mins compared to 1hr for Viagra.
  • Safe – approved for clinical use in the UK.
  • Easy to use – swallowing a simple 1-a-day pill.
  • Effective – 40-65% of those taking it can successfully attempt sex.
On average, Avanafil takes 15-30 minutes to take effect. This is about half the time that other ED treatments, like Viagra, take to work. When combined with sexual stimulation, Avanafil typically induces erections strong enough for penetration, for 4 hours or more.

What doses of Avanafil are available?

The initial dose for an adult over 18 years old is usually 100 mg, taken 15-30 minutes before sexual activity. Your doctor will help you decide on your first dose and on the next dose depending on how well this first dose works

There are three different doses of Avanafil available:

  • 50 mg.
  • 100 mg.
  • 200 mg.

Some men will find that they are able to achieve an erection strong enough for sexual activity on a lower dose of Avanafil. Other men may need a higher dose. The most Avanafil you can take per day is one dose (pill). So the most Avanafil any person should take is one pill of the strongest dose – 200 mg in 24 hours.

Avanafil is a medicine that should be taken on-demand, meaning 15-30 minutes prior to attempting sexual activity that requires an erection.

How well does Avanafil work and how long does it last?

The effectiveness of Avanafil is related to the size of the dose, meaning that on average, users taking a higher dosage are more likely to achieve an erection.This is not always the case, and will vary for each person.

No matter what the dose is, once Avanafil has taken effect it should last for around 6 hours.

According to recent studies, Avanafil is able to produce erections strong enough for sexual activity in:

  • 40-45% of men on a 50 mg dosage.
  • 55-60% of men on a 100 mg dosage.
  • 60-65% of men on a 200 mg dosage.

This is compared with 25-30% of men on a placebo pill (one containing no medication).

Avanafil has been found to be most effective in men with mild to moderate ED. Like Viagra and Cialis, eating a fatty meal before taking the medicine can affect how long it takes to work, although not as much.

What are the side effects?

Common (affecting 1 in 10) side effects for Avanafil include:

  • Headaches. 
  • A blocked nose.
  • Flushing (of the skin).

Uncommon (affecting 1 in 100) side effects include: 

  • Back pain.
  • Nausea.
  • Dizziness.
  • Tiredness.
  • Muscle cramps.
  • Changes in heartbeat.
Avanafil is not known to have an effect on your vision. This is an advantage over Viagra which has been found to affect vision in some people. If you experience any severe, unpleasant or unexpected side effects, speak to your GP as soon as possible. 

Where can I get Avanafil in the UK?

You can order Avanafil by getting a prescription from your GP and taking it to your local pharmacy, or by using an online doctor service. Most pharmacies will stock this medicine. Avanafil is a prescription medicine, and you should only take it if it has been prescribed to you by a doctor.

Avanafil prices vary in different pharmacies and online doctors. Superdrug Online Doctor prices for Avanafil are the cheapest available and start from just £49.

Who can take Avanafil?

Avanafil isn’t suitable for everyone. Your doctor will assess whether or not it is the right form of ED treatment for you.

You should not take Avanafil if you have certain medical conditions, including:

  • Severe heart or liver problems.
  • Having had a recent stroke or heart attack.

Will Avanafil interact with other medicines?

Avanafil may interact badly with other medicines. You should not take Avanafil if you are currently taking the following medicines, as they have been known to affect the way it works and can be dangerous:

  • Ketoconazole.
  • Itraconazole.
  • Ritonavir.
  • Diltiazem.
  • Fluconazole.
  • Verapamil.
  • Clarithromycin and erythromycin (antibiotics).
  • Nitrates.


Alwaal, A., Al-Mannie, R. and Carrier S. (2011). Future prospects in the treatment of erectile dysfunction: focus on avanafil. Drug Des, Dev and Ther, Oct; 5(1): 435-443. 

Corona, G, Maggi, M. and Jannini, E. A. (2016). Avanafil: the second-generation treatment of erectile dysfunction. Eur Med J, Aug; 1(3): 61-69.

Delvin, D. (2016). Avanafil. [online] NetDoctor. Available at: [Accessed 17 May 2017].

Eardley, I. et al (2010). Pharmacotherapy for Erectile Dysfunction. Sex Med, Jan; 7(1): 524-540.

Evans, J. D. and Hill, S. R. (2015). A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil. Pat Pref Adh, Aug; 9(12): 1159-1164.

Greenspan, M. B. and Barkin, J. (2012). Erectile dysfunction and testosterone deficiency syndrome: the “portal to men’s health”. Can J Ur, Oct; 19(1): 18-27.

Joint Formulary Committee, 2017. Avanafil. In: Joint Formulary Committee. British National Formulary. [online]. London: BMJ Group and Pharmaceutical Press. Available from: [Accessed 24 May 2017]. (2014). Erectile dysfunction: avanafil. [online] NICE. Available at: [Accessed 17 May 2017].