Acne Treatments
Request from a wide range of acne treatments to help reduce symptoms of all types of acne.
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Request treatment easily without any face-to-face appointments
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Effective treatments to help you manage and prevent acne
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Acne is a condition that affects millions of people worldwide. It usually affects teenagers and young adults but older adults can also have it. A wide range of treatments is available for acne, ranging from creams and tablets to lasers and extractions.
If you’re not sure if you have acne, you can get a quick diagnosis with our photo diagnosis service without booking an appointment or leaving your home.
Medically reviewed by
Dr Clair GraingerLast reviewed: 20 Mar 2026
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About Acne Treatment Options
What is acne?
Acne is a common inflammatory skin condition that’s caused when our hair follicles are blocked with dead skin cells and sebum. Sebum is a type of oil that is made by a gland in our follicles and helps to moisturise and protect our skin. Bacteria can also collect in the follicle, causing pus to form.
Acne often affects the face but can also affect other areas of the body like the back, chest, neck, shoulders, and upper arms. Acne can cause the skin to become red as well as causing spots, pimples, and cysts. It is treatable in many cases, although the most suitable treatment varies from case to case.
How common is acne?
Acne is quite common, affecting around 95% of people aged between 11 and 30 years old. How bad the acne can get can be very different from person to person. Most people will find that their acne clears up in early adulthood, but around 3% of people will continue to have acne when they are over 35 years old.
How is acne diagnosed?
A doctor can diagnose acne by looking at your skin, usually your face, neck, chest, and/or back, to identify specific acne lesions or spots, such as blackheads, whiteheads, pustules, and papules. The severity of acne is determined by the types and number of lesions you have. For example:
- mild acne – mostly whiteheads and blackheads with some papules and pustules
- moderate acne – lots of whiteheads and blackheads, and many papules and pustules
- severe acne – lots of large painful lesions, including papules, pustules, nodules and cysts, which can be painful
If you have mild acne, a pharmacist can usually diagnose it and suggest effective treatments, but for more moderate or severe acne, you should make an appointment with your GP.
Alternatively, you can get a diagnosis using our photo diagnosis service. It is quick and easy to use – just upload 2 photos of the affected area, and our doctors will provide a diagnosis and advice on what to do next, including acne treatments, within 24 hours.
What types of acne are there?
Acne can appear in different forms, and some of the most common types are listed here.
Blackheads
Blackheads are caused when a follicle becomes clogged by dead skin cells and sebum, and the follicle remains open. With the follicle open, the contents are exposed to air, allowing them to react with oxygen in the air. This causes the contents to turn black in a process known as oxidation.
Whiteheads
Whiteheads are similar to blackheads. The main difference between them is that the follicle is closed. With the follicle closed, oxidation does not occur, and the contents remain white instead of turning black.
Papules
Papules are small bumps on the skin that usually turn red and have no pus visible beneath the skin. With a papule, the contents of the plugged follicle have put enough pressure on the walls of the follicle to cause them to break. The contents then spill out into the surrounding area, causing irritation and tenderness to the surrounding tissues.
Pustules
A papule can sometimes turn into a pustule within a few days. The main difference between a pustule and a papule is that a pustule will contain pus that’s visible on the surface. Much like a papule, a pustule will typically have a red or pink base, although the centre of the bump will be white or yellow in colour.
Nodules
Nodules occur when clogged pores grow larger and become more irritated. One of the key differences between nodules and the acne types already mentioned is that nodules are deeper under the skin. They can be hard and painful.
Cysts
Cysts are the largest type of acne. They go even deeper than nodules do and often occur because of an infection. Cysts can be very painful to the touch and can also result in permanent scars.
What causes acne?
A hair follicle is a small opening in the outer layer of the skin. Individual hairs grow from the base of follicles and through the opening of the follicle on the skin surface. Next to our hair follicles are glands that make sebum and once secreted from the gland, sebum will usually travel up the hair follicle to the surface where it can nourish and protect the skin.
Sebum will sometimes not make it to the surface of the skin, becoming clogged in the follicle instead, potentially causing the follicle to become inflamed and swollen. Dead skin can also gather in the follicle, along with bacteria, and where bacteria collect you are also likely to find pus. The result is the spots and pimples that acne causes.
What can cause acne flare-ups?
Many people with acne will have periods where their acne is under control, only for it to flare up occasionally. During flare-ups, the patient can have more spots and the spots they have can become more severe. Certain triggers are known to cause acne flare-ups:
Hormonal changes
Teenagers are the most likely age group to have acne because of hormone changes in their bodies. During puberty, an increase in the levels of certain hormones causes the sebaceous glands to grow larger and start making more sebum. This increase in sebum production is one of the main causes of acne. Some people will go through hormone changes later in life that can cause acne, especially women, for example during pregnancy or at certain stages of their menstrual cycle.
Diet
Research suggests that high-glycemic-index foods and increased carbohydrate intake can contribute to acne, with one review showing that 77% of studies supported a link between high-glycemic foods and acne. These foods can cause your blood sugar and insulin levels to spike, which can promote the production of oil (sebum) in the skin, leading to inflammation and clogged pores. However, a low-glycemic diet over 12 weeks reduces total acne lesions by 51% and inflammatory lesions by 45% compared with a control.
Further research has also found that increased dairy intake is associated with acne development. However, the research is mixed, with some studies showing that low-fat or skimmed milk is more likely to contribute to acne than full-fat versions.
The National Institute for Health and Care Excellence (NICE) states that although high glycaemic index (GI) foods can make acne worse, the overall role of the diet in acne is poorly understood.
Food swaps to support acne-prone skin:
| Avoid | Swap |
|---|---|
| ✗ Refined carbohydrates – white bread, pasta, and rice | ✓ Whole grains – Brown bread, pasta, rice, quinoa, and oats |
| ✗ Cow’s milk – especially low-fat or skimmed milk | ✓ Plant milks – almond, coconut, oat, or soya |
| ✗ Sweets and pastries – sweets, candies, chocolates, biscuits, and cakes | ✓ Fruit and vegetables – berries, oranges, apples, carrots, sweet potatoes, spinach |
| ✗ Processed snacks – crisps, savoury biscuits, and crackers | ✓ Nuts and seeds – sunflower seeds, pumpkin seeds, almonds, walnuts, hazelnuts |
| ✗ Fizzy or high sugar drinks – cola, soda, fruit juices, energy drinks | ✗ Water and herbal tea – try adding a slice of fruit to plain water or swapping coffee for a herbal tea |
Medication
Some medicines can also trigger acne. Such medicines include, but are not limited to, some contraceptives, oral corticosteroids, and less commonly, some B vitamins.
Stress
Although stress will not cause acne, studies suggest that stress can make acne worse for people who already have it.
How is acne treated?
There is a large selection of acne treatments available, and which treatment is most suitable for you will depend on the severity of your case, among other factors. Our doctors will be able to recommend the most suitable option for your case.
Topical acne treatments
Topical treatments are applied directly to the affected skin. For people with mild-to-moderate acne, the doctor will recommend trying a single topical treatment, like benzoyl peroxide, a topical retinoid, an antibiotic cream in combination with benzoyl peroxide or a retinoid, or azelaic acid. They work in various ways, such as:
- killing bacteria and reducing inflammation
- unclogging pores
- reducing inflammation
- increasing skin cell turnover
Topical acne treatments are usually applied once or twice daily, at night, and can take 4 to 8 weeks to visibly improve your skin’s appearance. They can be very effective, with topical treatments containing azelaic acid reducing acne lesions by an average of 48%. A 10% benzoyl peroxide product can reduce acne-causing bacteria numbers by 98% in 2 weeks, making this an effective option for mild acne.
At Superdrug Online Doctor, we can offer the following topical treatments:
- Acnecide 5% gel
- Aknemycin Plus
- Clindamycin 1% + benzoyl peroxide 5% gel
- Differin cream
- Differin gel
- Epiduo Forte gel
- Epiduo gel
- Finacea gel
- Skinoren cream
- Treclin gel
- Zineryt solution (for pregnancy use only)
Antibiotic tablets for acne
Antibiotic tablets, such as lymecycline and doxycycline, are prescribed for moderate to severe acne, in combination with a topical treatment. They work by reducing bacteria on the skin that cause acne and by reducing inflammation. Antibiotics reduce the body’s inflammatory response, which reduces redness, swelling, and sebum production, helping prevent pores from becoming clogged.
Research shows that antibiotics, like lymecycline, can reduce acne severity by 42% in people with moderately severe acne. While doxycycline can reduce inflammatory lesions by up to 75%. Antibiotic tablets are usually prescribed for 3 to 6 months to treat acne, so it can take a while for you to notice improvements in your skin.
You’ll usually need to take the tablets once per day, as your doctor directs, but they will always be prescribed alongside a topical acne treatment. This is to help maximise the effectiveness of your treatment, speed up the healing process, and stop the bacteria from becoming resistant to antibiotics.
At Superdrug Online Doctor, we can provide the following antibiotic tablet and topical treatment combinations:
- Doxycycline + Skinoren 20% cream
- Doxycycline 100mg + Epiduo gel 0.1%
- Lymecycline 408mg + Skinoren 20% cream
- Lymecycline 408mg + Epiduo gel 0.1%
- Oxytetracycline 250mg + Epiduo gel 0.1%
Hormonal acne treatments
Hormonal treatment may work well for women with acne, especially if it flares up around the time of their period. Some combined contraceptive pills will reduce the levels of certain hormones known as androgens in the body. A reduction in androgens will, in turn, help to reduce how much sebum is produced, helping to control acne.
It’s important that combined contraceptive pills are used because they need to contain both oestrogen and progestogen to be effective. The mini pill, which contains only progestogen, may actually make acne worse.
Retinoid tablets
Retinoids are a group of drugs that are made from vitamin A. Vitamin A is important for healthy skin because it encourages the production of elastin and collagen, and retinoids encourage the production of new skin cells.
New skin cell growth will cause dead skin cells to be removed (exfoliation), helping to clear pores of dead skin cells and excess oil. Retinoids also help to reduce inflammation, reducing pain and irritation and helping to improve the appearance of the skin.
Isotretinoin is available as an oral retinoid capsule that is also available under the brand names Rizuderm, Reticutan, or Accutane. At Superdrug Online Doctor, we do not prescribe retinoid tablets for acne, but we can offer topical retinoid creams.
Over-the-counter acne treatments
Most people will use acne treatment that’s available without a prescription. Such treatments will usually be in the form of face washes or creams that are applied directly to the affected area and help to keep follicles clean of oil and debris, as well as helping to kill bacteria. It’s important not to over wash the face as acne is not caused by poor hygiene. Washing twice a day with a gentle soap or face wash is enough.
One of the most common ingredients in acne washes and creams is benzoyl peroxide (BP), which is an antibacterial agent. The effectiveness of non-prescription acne treatments varies. Those that contain active ingredients like BP are more likely to be effective.
Which acne treatment is right for me?
The treatment that is right for you will depend on how severe your acne is, the types of lesions you have, and even your skin type. Acne can range from mild to severe, and topical treatments are usually recommended for mild cases.
Over-the-counter treatments, such as benzoyl peroxide, can be given by a pharmacist, while prescription-strength creams and gels, such as topical retinoids, either alone or in combination with an antibiotic cream or azelaic acid, are usually used for more moderate cases.
If you have severe acne, such as cystic acne, you may be given oral antibiotics alongside a topical treatment to improve your skin.
Which acne treatment is right for you will depend on various factors, including the type of acne you have. If you are unsure of which treatment you need, our doctors will be able to recommend the most suitable treatment for you and give you a prescription if needed.
How can I prevent acne?
Acne is not down to poor hygiene, but regular cleaning can still help to keep acne under control. Wash the affected area regularly using a mild soap to avoid irritating the skin. Also, be mindful of which cosmetics or other products you are using on your face.
You should also try and identify triggers that might be causing flare-ups. Keeping a diary of your activities, including what you eat, can help you identify what makes your acne worse.
What are the side effects of acne treatment?
Potential side effects of topical acne treatments include:
- redness
- dryness
- irritation
- itching
- burning
- peeling
Potential side effects of antibiotic pills include:
- light-headedness
- upset stomach
- swelling
- tight throat
- breathlessness
It is also important to note that many of these treatments cannot be used if pregnant or breastfeeding, so you must talk to your doctor about which medication or cream is best for you.
For more information about the potential side effects of your medication, you should read the patient information leaflet that comes with it. Or, you can also ask your doctor for advice.
How long do these side effects last?
Most mild side effects, such as dryness, redness, or irritation, typically last 2 to 6 weeks as your skin adjusts to the active ingredients. In most cases, acne treatment side effects go away once the treatment has finished.
What to do if you get side effects
Most mild side effects can be managed at home in the following ways.
| Side effects | How to manage | |
|---|---|---|
| Oral antibiotics | Headaches | Take over-the-counter painkillers, drink plenty of water, and stay rested. |
| Feeling or being sick | Take the tablets or capsules with food, and eat smaller, more frequent meals. | |
| Stomach pain | Apply a warm compress to your stomach and speak to your doctor or pharmacist if it is severe or gets worse. | |
| Diarrhoea | Drink plenty of clear fluids to keep you hydrated. | |
| Topical antibiotics | Itching, pain, or burning | Apply a smaller amount of cream or gel, or reduce the number of times you apply it. If that does not help, stop using the treatment until the side effects pass. |
Rarely, acne treatments can cause serious side effects, like allergic reactions. If you get any of the following symptoms, stop using the treatment and call 999 or get someone to take you to A&E:
- your lips, mouth, throat, or tongue become swollen
- difficulty breathing or swallowing
- skin, tongue, or lips turn blue, grey, or pale
- confusion, drowsiness, or dizziness
- swollen, raised, itchy, blistered, or peeling skin
- rapid swelling under the skin (angioedema)
- eye swelling
- swelling face
Sources
- Multicenter study for efficacy and safety evaluation of a fixed dose combination gel, Anais Brasileiros de Dermatologia [accessed 17 February 2026]
- Association between stress and acne, Clinical, Cosmetic and Investigational Dermatology [accessed 17 February 2026]
- Zinc in Wound Healing Modulation, National Library of Medicine [accessed 17 February 2026]
- Diet and acne update: carbohydrates emerge as the main culprit, National Library of Medicine [accessed 17 February 2026]
- A randomized, single blind comparison of topical clindamycin + benzoyl peroxide (Duac) and erythromycin + zinc acetate (Zineryt) in the treatment of mild to moderate facial acne vulgaris, National Library of Medicine [accessed 17 February 2026]
- A comparison of the efficacy and safety of lymecycline and minocycline in patients with moderately severe acne vulgaris, National Library of Medicine [accessed 17 February 2026]
- Benzoyl peroxide, NHS [accessed 17 February 2026]
- Acne, NHS [accessed 17 February 2026]
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- A comparison of the efficacy and safety of lymecycline and minocycline in patients with moderately severe acne vulgaris, European Journal of Dermatology [accessed 17 February 2026]
- A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial, The American Journal of Clinical Nutrition [accessed 17 February 2026]
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- Benzoyl Peroxide, National Library of Medicine [accessed 17 February 2026]
- Consumption of dairy in teenagers with and without acne, Journal of the American Academy of Dermatology (JAAD) [accessed 17 February 2026]
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- Diet and acne: A systematic review, JAAD International [accessed 17 February 2026]
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