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pack of Trimethoprim 200mg tablets

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Trimethoprim

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Trimethoprim is an antibiotic that was used to treat cystitis in women. Now, recent guidelines from the National Institute of Health and Care Excellence show that Trimethoprim is no longer recommended for treating cystitis in the UK.

Now, the best antibiotic treatment recommended for cystitis is MacroBid (nitrofurantoin). Which you can order online through Superdrug Online Doctor

To place your order for alternative cystitis treatment, fill in our brief questionnaire and select your preferred treatment. Our doctor will check whether your symptoms indicate that you have cystitis and approve an appropriate treatment.

You can also order your treatment for future use, so you have it available when your symptoms first start.


Start Order for MacroBid

Start Order for Future Use

To place an order, fill in a brief questionnaire. One of our doctors will review your order and prescribe a suitable treatment.


6 tablets - three day course £25
6 tablets - for future use £25

Price includes prescription and delivery.

In a hurry? Choose Click and Collect and pick up your order after just 3 hours from a Superdrug Pharmacy.

Delivery options

Delivery method Cost Estimated delivery

You will choose your delivery option at the checkout. Delivery options may vary depending on the pack size and dosage chosen.

About Trimethoprim
Cystitis is caused by bacteria. Trimethoprim is an antibiotic, which used to be used to treat this infection. The standard dosage when taking trimethoprim for UTI (Urine Tract Infections) treatment was 200mg taken twice every day for three days. Please note, Trimethoprim is no longer recommended for treating cystitis in the UK.

How to take trimethoprim

Trimethoprim is usually taken twice a day when used to treat infections. The length of course will depend on the reason you’ve been prescribed your antibiotic.

The tablets need to be taken at the same time every day. You need to swallow each tablet whole with a glass of water. You can take the tablets with or without food. 

If you forget to take a tablet, just take the missed trimethoprim dose as soon as you remember and then continue treatment at the correct time, but do not take a double dose to make up for a forgotten dose.

It is very important that you take the full course you have been prescribed, even if your symptoms improve. Stopping treatment early could worsen your condition and it could mean that the bacteria which cause your infection become resistant to the antibiotic.

Trimethoprim and Alcohol

Trimethoprim does not interact with alcohol, which means that you can drink alcohol during your treatment. However, if you are taking trimethoprim for a UTI (urinary tract infection), you should avoid alcohol and ensure you drink plenty of clear fluids.

Who can take trimethoprim?

You mustn’t take trimethoprim if you are allergic to any of the ingredients in the tablets. The antibiotic is also not suitable for women who are pregnant, patients who have a blood disorder or severe kidney disease.

If you are having dialysis for your kidneys, are breastfeeding or are deficient in folic acid, make sure you mention this to your doctor before using trimethoprim.

Pregnancy and breastfeeding

Trimethoprim is not suitable for women who are pregnant. If you are breastfeeding, make sure your doctor knows before you start using trimethoprim.

Do I need a prescription?

Like most antibiotics, trimethoprim is only available on prescription. Your can visit your GP to see if you need trimethoprim. It is important that a doctor confirms that trimethoprim is suitable for you, as it may not be the right treatment for you, depending on your condition and medical history. 

Does trimethoprim affect the contraceptive pill?

Trimethoprim does not have any effect on the efficacy of the contraceptive pill or any other hormonal contraceptive. You won’t need to take additional precautions to avoid pregnancy while you are using trimethoprim.
Trimethoprim can cause side effects in some cases.

The following common side effects can occur:

  • trimethoprim can alter the numbers of certain blood cells, which might show up in blood tests
  • nausea and feeling sick
  • sore mouth
  • rash (mild to severe)
  • skin changes: itchy, scaly, flaking or swollen
  • circular red patches on your skin
  • Stevens-Johnson syndrome (a severe rash with flushing, fever, and blisters)
  • toxic epidermal necrolysis (a severe rash with red, peeling, swollen skin that looks as if it has been burned)
  • flushing, fever and ulcers
  • changes is your liver enzymes (which may show in tests)
  • jaundice (yellowing of the eyes)
  • cramps, muscle pain, an irregular heartbeat, tiredness or weakness (caused by high potassium)
  • headache
  • swollen tongue
  • increase of levels of creatinine or urea (which may show in kidney function tests)

Seek medical help immediately if and of these serious side effects occur:

  • you experience unusual bruising, throat infections or nose bleeds
  • you experience signs of an allergic reaction (such as swellings to the face or tongue, breathing problems, shock or fainting)
  • you experience a headache, fever, unusual sensitivity to sunlight, a stiff neck or you feel very ill (which could be caused by aseptic meningitis)

For a full list of side effects read the patient leaflet provided with your antibiotic.
Do not take Trimethoprim if you are taking:

  • certain antibiotics (for example rifampicin)
  • some malaria medications (for example pyrimethamine)
  • certain medications used to treat heart conditions (such as digoxin)
  • medications to stop your blood clotting (for example warfarin)
  • medications to prevent rejection after organ transplantation (for example ciclosporin)
  • medications used to treat epilepsy
  • bone marrow depressants

Tell your doctor about any other medication you are taking before beginning treatment with trimethoprim.

Trimethoprim cannot be taken by pregnant women and it is not suitable for patients with a blood disorder, a deficiency in folic acid or a severe kidney problem.
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4.8 Excellent

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    by , 30th Dec 2018
    Really disappointed.....

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    by , 13th Dec 2018
    excellent service highly recommended

  • 5
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    by , 30th Oct 2018
    Worked great, felt much better

  • 5
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    by , 27th Aug 2018
    Medication purchased did the job. Thanks.

  • 5
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    by , 30th Jun 2018
    Did the job when nothing else did!!

  • 5
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    by , 13th Mar 2018
    These guys were amazing. Thanks for a brilliant service

  • 5
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    by , 7th Mar 2018
    Absolutely awesome service, got antibiotics so quickly and healed much faster than waiting for the GP to answer n get an app Monday morning.! Fantastic back up service, have recommended to all my friends n family. This is the future.

  • 5
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    by , 16th Jan 2018
    Fast easy service. Would recommend.

  • 5
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    by , 14th Jan 2018
    Easy and straightforward to order and a quick delivery

  • 5
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    by , 27th Dec 2017
    Excellent service and product.

  • 5
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    by , 11th Dec 2017
    Really helpful service which I used when I was not able to get to the doctor. Thank you. The only glitch was that my address didn't seem to connect with the one held by the Superdrug pharmacy in Worcester Park but that was resolved. S.O.

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    by , 3rd Nov 2017
    Would use again without doubt.

  • 5
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    by , 2nd Nov 2017
    So convenient. Instant reply from doctor.

  • 5
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    by , 22nd Oct 2017
    An excellent service; ordered medication, had confirmation it had been authorised and then collected from local store. Very quick and easy.

  • 5
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    by , 20th Oct 2017
    Quick and easy way for me to get what I need

  • 5
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    by , 4th Oct 2017
    Absolute life savers!! These little beauties start working within just a couple of hours of taking one! I couldn't be without these when I have a water infection out of the blue. Would recommend to anyone who suffers.

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    by , 22nd Sep 2017
    Great easy and quick service

  • 5
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    by , 22nd Aug 2017
    Could feel relief within a few hours of taking one dose.

  • 5
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    by , 21st Aug 2017
    Quick online prescription and easy pick up. My partner was able to get it too as I couldn't.

  • 5
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    by , 30th Jul 2017
    Great online service & fast delivery. Would have been better if I could have collected from a Sheffield store.

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    by , 18th Jul 2017
    Excellent. Would definitely use again when needed.

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    by , 4th May 2017
    Felt better within the day ....so easy as I was visiting from overseas with no gp

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    by , 24th Mar 2017
    Very easy and quick to order. Saved the hassle of organising a dr appointment.

  • 5
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    by , 19th Mar 2017
    Great service product was ready and waiting within 2 hours of going online.

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    by , 6th Mar 2017
    Product didn't work and cost £25!! All because I couldn't get into my doctors. What a waste of time

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    by , 4th Nov 2016
    Product was fine. Delivery was very slow though.

  • 5
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    by , 8th Sep 2016
    Excellent quick and efficient service.

  • 5
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    by , 2nd Sep 2016
    Excellent service , will use again

  • 5
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    by , 16th Aug 2016
    Very convenient, great when I was travelling and couldn't get to my doctors.

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    by , 7th Aug 2016
    Good fast trusted service and product was as requested. However if I had been able to get a GP appointment at my local surgery, I would not have needed this service.

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    by , 5th Aug 2016
    Good quick service for the times when you need an easy prescription and you'd have to wait a week to see a GP. Bit pricey, but useful and speedy.

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    by , 19th Jul 2016
    I was a new customer, but it was easy to register and order what I needed. After answering some questions about my symptoms it was sorted. Went to the superdrug in Bridlington my prescription was ready and waiting. Very nice pharmacist. Sorted.

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    by , 18th Jul 2016
    Worked well against uti cleared up quickly.

  • 5
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    by , 25th Jun 2016
    Absolutely excellent service

  • 5
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    by , 12th Jun 2016
    What a great service when I needed medication urgently

  • 5
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    by , 11th Jun 2016
    It was so easy to get the prescription drugs I so needed quickly. I ordered them and within three hours I picked them up from my local superdrug ...A big thankyou .

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    by , 4th Jun 2016
    Very happy with the service and product. Tablets were very effective. Placed order at 11.30 and picked up order at 3.30. Own doctors couldn't get appointment for 10 days and was in no fit state to go out. So thank you superdrug and doctors involved. Would use service again..brilliant..(I did know what the medical problem was so knew what to order).

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    by , 27th Mar 2016
    Great quick deliveries promised

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    by , 14th Mar 2016
    Brilliant had the worst water infection ever got my antibiotics next day got rid ov it really quickly

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