The ingredients of Estriol cream means that it may not work for everyone. This may be due to having a certain health condition or taking medications that could interact with Estriol cream, which can reduce its effectiveness or make it unsafe to use.
Contraindications to Estriol Cream
You should not use Estriol cream if you are under 18, pregnant or breastfeeding. Before you start using the cream, your doctor must know if:
- You are allergic to soy or peanuts.
- You or a close relative have had breast cancer or you think you may have breast cancer.
- You have or have had endometrial cancer or any other cancer that is made worse by oestrogens.
- You have or have ever had endometriosis, fibroids in your womb or endometrial hyperplasia.
- You have ever had blood clots or have an abnormality that makes you prone to developing them.
- You have had a heart attack or angina.
- You have a blood problem called ‘porphyria’
- You have abnormal vaginal bleeding for unknown reasons.
- You have acute liver disease or a history of liver disease which is not completely resolved.
There are other conditions such as diabetes or gallstones that mean you may require closer monitoring when using Estriol cream. It’s important that you let your doctor know of any health conditions before you start using Estriol cream.
Interactions with Estriol Cream:
Estriol is absorbed into the bloodstream through the vagina in low amounts, so the chances of it interacting with other medications you are taking are low. However, if you use other vaginal medications, like creams or pessaries for thrush and other infections, your doctor may recommend that you avoid using Estriol cream until you finish your treatment. There is also potential for Estriol cream to reduce the effects of Lamotrigine, a medication used in epilepsy. It is important to always tell your doctor which medications you are using.
You can use lubricants and moisturisers alongside Estriol cream. Estriol cream can damage diaphragms and condoms, reducing their effectiveness against STIs or pregnancy.
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