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pack of Circadin melatonin tablets for jet lag

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pack of Circadin melatonin tablets for jet lag
Circadin is a medication which contains the hormone melatonin. Melatonin naturally occurs in the human body and is involved in regulating our sleep-wake cycle. It can be taken to overcome the effects of jet lag when travelling.

To buy melatonin tablets you need a prescription. Order your tablets online - our service is fast and convenient. Just fill in our brief medical questionnaire and our online doctor will check your information and approve an appropriate treatment. 

Melatonin is currently not licensed for use in jet lag in the UK. It is licensed for use to treat insomnia, but a large scientific review has approved its use for prevention of jet lag.

Start Order

To place an order, fill in a brief questionnaire. One of our doctors will review your order and prescribe a suitable treatment.

Circadin 10 tablets £27.50
Circadin 20 tablets £40.00

Prices include prescription and delivery.

In a hurry? Choose Click and Collect and pick up your order after just 4 hours from a Superdrug Pharmacy.

Delivery options

Delivery method Cost Estimated delivery

You will choose your delivery option at the checkout. Delivery options may vary depending on the pack size and dosage chosen.

Order Circadin Melatonin Tablets

What is Melatonin?

The active ingredient in Circadin is melatonin. Melatonin is a hormone which naturally occurs in the human body. Blood levels of the hormone vary throughout the day and regulate our sleep-wake cycle. The amount of melatonin which is released depends on cues such as daylight. During daytime, the production of melatonin is inhibited. When it gets dark, the production increases and causes you to feel tired and sleepy and prepares your body for rest.

When crossing several time zones, travellers often suffer from jet lag. This is due to the fact that your internal “body clock” (circadian rhythm) has to adjust to a new time zone and produce melatonin at a different time than your body is used to. Taking melatonin tablets can help you overcome the time difference by helping you go to sleep when it is nighttime at your travel destination. As a result, you quickly settle into the new routine.

How is Circadin taken?

Circadin prolonged-release tablets need to be taken 1 - 2 hours before going to sleep. Swallow the tablet whole with water. You should take it after food. When you order Circadin to reduce the effects of jet lag, our online doctor will prescribe a packet of tablets to help you regulate your sleeping pattern during your first few days in the new time zone. Do not take more than one tablet of melatonin per day. If you have forgotten one dose, just miss that dose and take one tablet the next night if needed. Do not double the dose to make up for a missed tablet.

Please note that jet lag is an ‘off-label’ use for Circadin. All medications we offer are fully licensed within the UK. Some medications, such as this, we prescribe for conditions, or circumstances that are outside of the license also known as ‘off-label’. Prescribing ‘off-label’ is common practice by healthcare professionals to ensure a medication can safely benefit as many patients as possible. This is always based on updated information and evidence since the product first became available.

Who can take Circadin?

You mustn’t take Circadin if you are allergic to melatonin or any of the other ingredients. 

Before taking Circadin, make sure you tell your doctor if you:

Have a kidney or liver problem

Have an intolerance to some sugars

Have an autoimmune disease

Please note: Circadin can make you feel drowsy. Don’t drive if you feel that your treatment is impairing your ability to drive.

Smoking tobacco can impair the effectiveness of melatonin. To get the best effect from your treatment, quit smoking.

How does Circadin work?

Circadin contains melatonin, a hormone which regulates your sleep-wake cycle. When you travel across several time zones, your sleep-wake cycle is out of synch with the local time. This can make it difficult to sleep when it is night time at your destination.

Taking Circadin helps you sleep and allows you to adjust to the local time zone quicker. 

When taking Circadin for jet lag, you will take one tablet which contains 2mg of the active ingredient melatonin. You can stop your treatment when you feel that you have adapted to the new time zone - you will not experience any withdrawal symptoms or problems sleeping as a result of taking melatonin tablets.

Side Effects

Circadin can cause side effects in some people. If you experience the following side effects while taking melatonin tablets, contact a doctor immediately:

  • chest pain
  • palpitations
  • visual disturbances
  • depression
  • dizziness or a spinning sensation
  • depression
  • feeling disoriented
  • blood cells in your urine
  • changes in your blood levels of certain cells (may show in blood tests)
  • increased bleeding or bruising
  • psoriasis

Circadin is usually tolerated well and does not commonly cause side effects.

Uncommon Side Effects of Circadin

  • changes in mood such as irritability, restlessness and nervousness
  • insomnia, unusual dreams and nightmares
  • headaches and migraine
  • lethargy and tiredness
  • dizziness
  • high blood pressure
  • abdominal pain and indigestion
  • mouth ulcers
  • changes in the composition of your blood (will show in blood tests)
  • jaundice (yellowing of skin and eyes)
  • inflammation of the skin, dry skin, itchy skin or skin rash
  • night sweats
  • pain in the extremities
  • feeling weak
  • abnormal liver function
  • excretion of glucose in the urine
  • excess excretion of proteins in the urine
  • weight gain
  • menopausal symptoms

Do not drive or operate machinery if Circadin is making you feel drowsy.

For all known side effects of Circadin, read the patient leaflet supplied with your melatonin tablets.

Drug Interactions

Melatonin tablets can interact with other medications.

This includes:

  • oestrogens (for example the contraceptive pill and medications used for hormone replacement therapy)
  • other sleeping tablets and sedatives
  • beta-blockers and other blood pressure medications
  • alcohol
  • prostaglandin inhibitors (including non-steroidal anti-inflammatories)
  • fluvoxamine (used to treat psychiatric conditions) and some other anti-depressants
  • psoralens (used to treat certain skin conditions)
  • cimetidine
  • quinolones
  • rifampicin
  • the epilepsy medication carbamazepine
  • thioridazine (used to treat schizophrenia)
  • imipramine (for the treatment of depression)
  • adrenergic agonists/antagonists (used to treat a range of conditions, including high blood pressure and nasal congestion)
  • opiate agonists/antagonists (used to treat drug addiction)
  • tryptophan
  • benzodiazepines and non-benzodiazepine hypnotics

Do not take melatonin tablets if you are allergic to melatonin or any other ingredient in the tablets.

Avoid smoking tobacco and drinking alcohol while taking melatonin, as both reduce the effect of the medication.

Tell your doctor if you suffer from:

  • liver or kidney problems
  • an intolerance to certain sugars
  • an autoimmune disease
  • epilepsy